Search results for " Candida species"

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Procalcitonin as a marker of Candida species detection by blood culture and polymerase chain reaction in septic patients

2014

Background: The aim of our study is to test procalcitonin (PCT) as surrogate marker of identification of Candida spp. by blood culture (BC) and real-time-polymerase chain reaction (PCR), whether alone or in association with bacteria, in septic patients.Methods: We performed a single-centre retrospective study. We reviewed the clinical charts of patients with a diagnosis of severe sepsis or septic shock treated at our general intensive care unit from March 2009 to March 2013. We analysed all diagnostic episodes consisting of BC, real-time PCR assay and dosage of PCT. We registered age, sex, white blood count, sequential organ failure assessment score and type of admission between medical or …

Fungal infectionMalePathologyProtein PrecursorSettore MED/41 - AnestesiologiaProcalcitoninlaw.inventionRetrospective StudielawBlood cultureAntifungal therapyPolymerase chain reactionCandidaAged 80 and overmedicine.diagnostic_testbiologyMiddle AgedShock SepticPolymerase chain reactionBlood stream infectionReal-time polymerase chain reactionFemaleProcalcitoninProcalcitonin Sepsis Candida species Blood stream infection Fungal infection Polymerase chain reaction Antifungal therapyhormones hormone substitutes and hormone antagonistsResearch ArticleHumanCalcitoninmedicine.medical_specialtySepsiCalcitonin Gene-Related PeptideReal-Time Polymerase Chain ReactionMicrobiologySepsisSepsisparasitic diseasesCandida speciesmedicineHumansProtein PrecursorsMED/41 - ANESTESIOLOGIAAntifungal therapy; Blood stream infection; Candida species; Fungal infection; Polymerase chain reaction; Procalcitonin; SepsisRetrospective StudiesAgedbusiness.industrySurrogate endpointBiomarkerbacterial infections and mycosesmedicine.diseasebiology.organism_classificationAnesthesiology and Pain MedicineCalcitoninCandida speciebusinessBiomarkersBacteriaBMC Anesthesiology
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Potential association of specific Candida parapsilosis genotypes, bloodstream infections and colonization of health workers' hands.

2014

AbstractFungal nosocomial infections continue to be a serious problem among hospitalized patients, decreasing quality of life and adding millions of euros to healthcare costs. The aim of this study was to describe the pattern of fungi associated with the hands of healthcare workers and to genotype Candida parapsilosis isolates in order to understand whether their high clinical prevalence stems from endemic nosocomial genotypes or from the real emergence of epidemiologically-unrelated strains. Approximately 39% (50/129) of healthcare workers were positive for yeasts and among 77 different fungal isolates recovered, C. parapsilosis was the most frequent (44/77; 57%). Twenty-seven diverse geno…

Microbiology (medical)Candida parapsilosismicrosatellite genotypingSettore MED/17 - Malattie InfettiveGenotypeSepsiHospitalized patientsHealth PersonnelFungal pathogenNosocomial fungal infectionInfectious DiseaseBiologyCandida parapsilosisPersistence (computer science)MicrobiologyCandida parapsilosis; Candida species; Candidaemia; fungal pathogens; healthcare workers; microsatellite genotyping; nosocomial fungal infectionsCandidaemiaRetrospective Studienosocomial fungal infectionsSepsisGenotypeCandida speciesDisease Transmission InfectiousHumansColonizationDNA FungalMycological Typing TechniquesCandidaRetrospective StudiesGenetic diversityCross InfectionMolecular Epidemiologyhealthcare workersMedicine (all)Candida parapsilosis; Candida species; Candidaemia; Fungal pathogens; Healthcare workers; Microsatellite genotyping; Nosocomial fungal infections; Candida; Cross Infection; DNA Fungal; Disease Transmission Infectious; Genotype; Hand; Humans; Molecular Epidemiology; Molecular Typing; Mycological Typing Techniques; Retrospective Studies; Sepsis; Health Personnel; Microbiology (medical); Infectious Diseases; Medicine (all)General Medicinebiology.organism_classificationHandMolecular TypingInfectious DiseasesDisease Transmission InfectiouMicrosatellite AnalysisCandida specieHealthcare workerCandida parapsilosiMycological Typing Techniquefungal pathogensHumanClinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
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